Description – Tiromel
Manufacturer: Abdi Ibrahim
Pharmaceutical name: Liothyronine Sodium
Pack: 100 tabs (25 mcg/tab)
Average Dose: 25-100 mcg/day
Tiromel is a thyroid hormone. As a substance it contains synthetically manufactured liothyronine sodium which resembles the natural thyroid hormone tricodide-thyronine. The thyroid of a healthy person usually produces two hormones, the better known L-thyroxine and the aforementioned L-triiodine-thyronine. Since Tiromel is the synthetic equivalent of the latter hormone, it causes the same processes in the body as if the thyroid were to produce more of the hormone. It is interesting to note that L-Tiromel is clearly the stronger and more effective of these two hormones. This makes Tiromel more effective than the commercially available L-T4 compounds such as L-thyroxine or T4.
Bodybuilders take advantage of these characteristics and stimulate their metabolism by taking Tiromel, which causes a faster conversion of carbohydrates, proteins and fats. Bodybuilders, of course, are especially interested in an increased lipolysis, which means increased fat burning. Competing bodybuilders, in particular, use Tiromel during the weeks before a championship since it helps to maintain an extremely low fat content, without necessitating a hunger diet. Athletes who use low dosages of Tiromel report that by the simultaneous intake of steroids, the steroids become more effective, most likely as the result of the faster conversion of protein.
It is important to stress that a cycle should last no longer than 6 weeks and it should never be halted abruptly. As slowly as the dosage was built up it should also be lowered, one tablet every 3-4 days. Taking Tiromel for too long and/or at too high a dosage can result in a permanent thyroid deficiency. After doing such, one might need to be treated with a drug like Tiromel for life. It is also a good idea to first consult your physician and have your thyroid function tested. An undiagnosed hyperfunction would not mix well with the added hormone. An athlete should also be sure never to purchase an injectable form of the drug. It is generally an emergency room product, much too powerful for athletic use. Since Tiromel is the most powerful thyroid hormone athletes are using, this is generally not the starting point for a beginner. Before using such a powerful item, it is a good idea to become familiar with a weaker substance. An in-between point is T4 (L-Thyroxin 100) (synthetic T-4), still weaker in action than Tiromel. Once the user is ready however, the fat burning effect of this hormone can be extremely dramatic.
Until recently, Tiromel was used by bodybuilders and female bodybuilders, in particular on a daily basis over several months to remain “hard” and in good shape all year round. Believe us when we tell you that to a great extent several bodybuilders who are pictured in “muscle magazines” and display a hard and defined look in photos, eat fast food and iron this out by taking Tiromel. The over stimulated thyroid burns calories like a blast furnace. Nowadays, instead of Tiromel, athletes use Clenbuterol which is becoming more and more popular. Those who combine these two compounds will burn an enormous amount of fat.
Tiromel is also popular among female bodybuilders. Since women generally have slower metabolisms than men, it is extremely difficult for them to obtain the right form for a competition given todays standards. A drastic reduction of food and calories below the 1000 calorie/day mark can often be avoided by taking Tiromel. Women, no doubt, are more prone to side effects than men but usually get along well with 50 mcg/day. A short-term intake of Tiromel in a reasonable dosage is certainly “healthier” than an extreme hunger diet.
As for the dosage, one should be very careful since Tiromel is a very strong and highly effective thyroid hormone. It is extremely important that one begins with a low dosage, increasing it slowly and evenly over the course of several days. Most athletes begin by taking one 25 mcg tablet per day and increasing this dosage every three to four days by one additional tablet. A dose higher than 100 mcg/day is not necessary and not advisable. It is not recommended that the daily dose be taken all at once but broken down into three smaller individual doses so that they become more effective. It is also important that Tiromel not be taken for more than six weeks. At least two months of abstinence from the drug needs to follow. It is also important that the dosage is reduced slowly and evenly by taking fewer tablets and not be ended abruptly.
One should take caution if considering using this drug. Tiromel comes with an extensive list of warnings and precautions which are not to be ignored. Side effects include, but are not limited to, heart palpitations, agitation, shortness of breath, irregular heartbeat, sweating, nausea, headaches, and psychic/metabolic disorders. It is a powerful hormone, and one that could potentially alter the normal functioning of the body if misused. When administering Tiromel, one must remember to increase the dosage slowly. Generally one 25 mcg tablet is taken on the first day, and the dosage is thereafter increased by one tablet every three of four days for a maximum dosage of 100 mcg. This will help the body adjust to the increased thyroid hormone, hopefully avoiding any sudden “shock” to the system. The daily dose is also to be split evenly throughout the day, in an effort to keep blood levels steadier. Women are more sensitive to the side effects of Tiromel than men, and usually opt to take no more than 50 mcg daily.
Replacement therapy in hypothyroidism, Severe and chronic hypothyroidism, TSH suppression, Myxoedema coma
Untreated hyperthyroidism; uncorrected adrenal failure; recent MI.
Nervousness, excitability, tremor, muscle weakness, cramps; sweating, flushing, heat intolerance, headache, insomnia, tachycardia, palpitations, angina pectoris, excessive wt loss; menstrual irregularities; diarrhoea, vomiting. Potentially Fatal: Convulsions, cardiac arrhythmia, heart failure, coma.
Reduced absorption with iron, colestyramine, colestipol, aluminium- and magnesium-containing antacids, calcium carbonate, simethicone, sucralfate. May alter requirements of antidiabetic drugs. Reduced efficacy of thyroid replacement therapy with imatinib. Reduced tri-iodothyronine serum levels with amiodarone. Reduced serum levels of thyroxine with carbamazepine, phenytoin, phenobarbital, rifampicin, oestrogens. Potentially Fatal: Increased therapeutic and toxic effects of levothyroxine and TCAs. May change hypoprothrombinaemic response to warfarin and other oral anticoagulants (markedly increased response during replacement). Increased risk of significant hypertension and tachycardia with ketamine.
Angina, heart failure; DM; diabetes insipidus; elderly; long-standing hypothyroidism; adrenal insufficiency; myxoedema.
Tiromel by Abdi Ibrahim is a synthetically manufactured prescription thyroid hormone. It specially consists of the L-isomer of the natural thyroid hormone triiodothyronine (T3). Thyroid hormones stimulate basal metabolic rate, and are involved with many cellular functions including protein, fat, and carbohydrate metabolism. Tiromel by Abdi Ibrahim is used medically to treat hypothyroidism, a condition where the thyroid gland does not produce sufficient levels of thyroid hormone. Hypothyroidism is usually diagnosed with a serum hormone profile (T3, T4, & TSH), and may manifest itself with symptoms including loss of energy, lethargy, weight gain, hair loss, and changes in skin texture. T3 is the most active thyroid hormone in the body, and consequently Tiromel by Abdi Ibrahim is considered to be a more potent thyroid medication than levothyroxine sodium (T4).
Bodybuilders and athletes are attracted to Tiromel by Abdi Ibrahim for its ability to increase metabolism and support the breakdown of body fat. Most often utilized during contest preparation or periods of “cutting”. Tiromel by Abdi Ibrahim is usually said to significantly aid in the loss of fat, often on higher levels of caloric intake than would normally be permissive of such fat loss. To this end, Tiromel by Abdi Ibrahim is also commonly used in conjunction with other fat loss agents such as human growth hormone or beta agonists. Some users also ascribe an ability of thyroid hormones like Tiromel by Abdi Ibrahim to increase the anabolic effect of steroids.
The usual protocol among bodybuilders and athletes taking Tiromel by Abdi Ibrahim to accelerate fat loss involves initiating its use with a dosage of 25 mcg per day. This dosage may be increased by 25 mcg every 4 to 7 days, usually reaching a maximum of no more than 75 mcg of Tiromel by Abdi Ibrahim per day. As in a medical setting, the intent of this slow buildup is to help the body become adjust to the increasing thyroid hormone levels, and avoid sudden changes that may initiate side effects. Cycles of Tiromel by Abdi Ibrahim usually last no longer than 6 weeks, and administration of Tiromel by Abdi Ibrahim should not be halted abruptly. Instead, Tiromel by Abdi Ibrahim is discontinued in the same slow manner in which it was initiated. This usually entails reducing the dosage by 25 mcg every 4 to 7 days. This tapering is done so that the body has time to readjust its endogenous hormone production at the conclusion of therapy, and to avoid the onset of side effects.
Triiodothyronine, also known as T3, is a thyroid hormone. It affects almost every physiological process in the body, including growth and development, metabolism, body temperature, and heart rate.
1. Production of T3 and its prohormone thyroxine (T4) is activated by thyroid-stimulating hormone (TSH), which is released from the pituitary gland. This pathway is regulated via a closed-loop feedback process: Elevated concentrations of T3, and T4 in the blood plasma inhibit the production of TSH in the pituitary gland. As concentrations of these hormones decrease, the pituitary gland increases production of TSH, and by these processes, a feedback control system is set up to regulate the amount of thyroid hormones that are in the bloodstream.
As the true hormone, the effects of T3 on target tissues are roughly four times more potent than those of T4.
2. Of the thyroid hormone that is produced, just about 20% is T3, whereas 80% is produced as T4. Roughly 85% of the circulating T3 is later formed in the thyroid by removal of the iodine atom from the carbon atom number five of the outer ring of T4. In any case, the concentration of T3 in the human blood plasma is about one-fortieth that of T4. This is observed in fact because of the short half-life of T3, which is only 2.5 days.
3. This compares with the half-life of T4, which is about 6.5 days.
Wikipedia link :
L-Triodotironin Sodium 25mg, 100 tablets (Abdi Ibrahim)
Tiromel (T3), brand name for substance liothyronine sodium is a thyroid hormone. It is used to treat thyroid insufficiency (hypothyroidism). Taking of T3 causes a faster conversion of carbohydrates, proteins, and fats. Body builders are especially interested in an increased lipolysis, which means increased fat burning and use it during the weeks before an event without hunger diet. Combination of T3 and Clenbuterol is one of the most popular fat burning stacks and it will burn an enormous amount of fat in a short time of period.
Recommended dosage :
One should be very careful since T3 is a very strong thyroid hormone. It is very important that person begins with a low dosage, increasing dosage slowly. Most athletes begin by taking one 25 mcg tablet per day and increasing this dosage every three to four days by one additional tablet. It is not recommended that the daily dose be taken all at once but broken down into three small doses. It is also important that T3 not be taken for more than six weeks and that the dosage is reduced slowly.Those who take high dosages of Tiromel over a long period of time are at risk of developing a chronic thyroid insufficiency. Possible side effects are trembling of hands, nausea, headaches, high perspiration, and increased heartbeat.